Abstract | ETHNOPHARMACOLOGICAL RELEVANCE: METHODS: The antidiarrheal activity was evaluated using castor oil-induced diarrhea method. In this respect, rats were divided into six groups: Control, Castor oil, Castor oil+Loperamide (LOP) and Castor oil+various doses of CDE. Animals were per orally (p.o.) pre-treated with CDE during 1h and intoxicated for 2 or 4h by acute oral administration of castor oil. RESULTS: CONCLUSION:
|
Authors | Hichem Sebai, Mohamed-Amine Jabri, Abdelaziz Souli, Kais Rtibi, Slimen Selmi, Olfa Tebourbi, Jamel El-Benna, Mohsen Sakly |
Journal | Journal of ethnopharmacology
(J Ethnopharmacol)
Vol. 152
Issue 2
Pg. 327-32
(Mar 14 2014)
ISSN: 1872-7573 [Electronic] Ireland |
PMID | 24463157
(Publication Type: Comparative Study, Journal Article, Research Support, Non-U.S. Gov't)
|
Copyright | Copyright © 2014 Elsevier Ireland Ltd. All rights reserved. |
Chemical References |
- Antidiarrheals
- Antioxidants
- Plant Extracts
- Loperamide
- Castor Oil
|
Topics |
- Administration, Oral
- Animals
- Antidiarrheals
(administration & dosage, isolation & purification, pharmacology)
- Antioxidants
(administration & dosage, isolation & purification, pharmacology)
- Castor Oil
(pharmacology)
- Diarrhea
(drug therapy)
- Disease Models, Animal
- Dose-Response Relationship, Drug
- Loperamide
(pharmacology)
- Male
- Matricaria
(chemistry)
- Medicine, Traditional
- Oxidative Stress
(drug effects)
- Plant Extracts
(administration & dosage, isolation & purification, pharmacology)
- Rats
- Rats, Wistar
- Time Factors
- Tunisia
|