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Single institutional experience using biological mesh for abdominal wall reconstruction.

AbstractBACKGROUND:
Complex ventral hernias remain a challenge. We present a study evaluating outcomes of complex ventral hernia repair using human-derived acellular dermal matrix (AlloDerm) and porcine-derived acellular dermal sheet (Permacol).
METHODS:
A retrospective review of 251 patients undergoing complex hernia repair was performed. Primary outcome was hernia recurrence; and secondary outcomes included early and late complications and mortality.
RESULTS:
Recurrence for Permacol versus AlloDerm was 32% versus 47% (P = .02). There was a difference in early complications (48% vs 30%, P = .007) and also late complications (30% vs 21%, P = .16) of Permacol versus AlloDerm. Overall survival was 85% for the Permacol group versus 78% for the AlloDerm group (P = .23). Recurrence for Permacol versus AlloDerm for underlay technique was 19% versus 22% and that for bridging technique was 44% versus 57%.
CONCLUSION:
There exists a high complication rate from both Permacol and AlloDerm in complex ventral hernia repair especially when used as a fascial bridge.
AuthorsAnthony Iacco, Adewunmi Adeyemo, Thomas Riggs, Randy Janczyk
JournalAmerican journal of surgery (Am J Surg) Vol. 208 Issue 3 Pg. 480-4; discussion 483-4 (Sep 2014) ISSN: 1879-1883 [Electronic] United States
PMID24462172 (Publication Type: Comparative Study, Evaluation Study, Journal Article)
CopyrightCopyright © 2014 Elsevier Inc. All rights reserved.
Chemical References
  • Alloderm
  • Permacol
  • Collagen
Topics
  • Abdominal Wall (surgery)
  • Adult
  • Aged
  • Collagen
  • Female
  • Hernia, Ventral (surgery)
  • Herniorrhaphy (instrumentation, methods)
  • Humans
  • Kaplan-Meier Estimate
  • Male
  • Middle Aged
  • Postoperative Complications (epidemiology)
  • Proportional Hazards Models
  • Recurrence
  • Retrospective Studies
  • Surgical Mesh
  • Treatment Outcome

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