Abstract | BACKGROUND: Complex ventral hernias remain a challenge. We present a study evaluating outcomes of complex ventral hernia repair using human-derived acellular dermal matrix ( AlloDerm) and porcine-derived acellular dermal sheet ( Permacol). METHODS: A retrospective review of 251 patients undergoing complex hernia repair was performed. Primary outcome was hernia recurrence; and secondary outcomes included early and late complications and mortality. RESULTS: Recurrence for Permacol versus AlloDerm was 32% versus 47% (P = .02). There was a difference in early complications (48% vs 30%, P = .007) and also late complications (30% vs 21%, P = .16) of Permacol versus AlloDerm. Overall survival was 85% for the Permacol group versus 78% for the AlloDerm group ( P = .23). Recurrence for Permacol versus AlloDerm for underlay technique was 19% versus 22% and that for bridging technique was 44% versus 57%. CONCLUSION:
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Authors | Anthony Iacco, Adewunmi Adeyemo, Thomas Riggs, Randy Janczyk |
Journal | American journal of surgery
(Am J Surg)
Vol. 208
Issue 3
Pg. 480-4; discussion 483-4
(Sep 2014)
ISSN: 1879-1883 [Electronic] United States |
PMID | 24462172
(Publication Type: Comparative Study, Evaluation Study, Journal Article)
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Copyright | Copyright © 2014 Elsevier Inc. All rights reserved. |
Chemical References |
- Alloderm
- Permacol
- Collagen
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Topics |
- Abdominal Wall
(surgery)
- Adult
- Aged
- Collagen
- Female
- Hernia, Ventral
(surgery)
- Herniorrhaphy
(instrumentation, methods)
- Humans
- Kaplan-Meier Estimate
- Male
- Middle Aged
- Postoperative Complications
(epidemiology)
- Proportional Hazards Models
- Recurrence
- Retrospective Studies
- Surgical Mesh
- Treatment Outcome
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