HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

From bare to covered: 15-year single center experience and follow-up in trans-catheter stent implantation for aortic coarctation.

AbstractBACKGROUND:
Bare stents has become the first line therapy for aortic coarctation. Covered stents has been reported more recently in clinical practice.
OBJECTIVES:
The present study, reports comparatively 15-year experience of bare and covered stent implantation for aortic coarctation in a single tertiary referral center.
METHODS:
From 1997 to 2011, 143 patients with native or postoperative aortic coarctation were treated at our institution. Seventy-one subjects (median age 17 years (range from 4 to 70 years) underwent bare stent implantation (Group 1) while 72 patients (median age of 17.5 years (range from 6 to 68 years) underwent covered stent implantation (Group 2).
RESULTS:
Success rate in the whole group was 95%. More complex and tighter coarctations were treated using covered stents. Incidence of related-procedure adverse events was higher in Group 1 than in group 2 (21.1% vs. 8.3% P = 0.035). Aortic wall complications occurred in 7% of patients in Group 1 (one death) and 0% in Group 2 (P = 0.028). Subjects in Group 1 had a longer follow-up (median 85 vs. 35 months; P < 0.001). Independent predictors associated with reintervention included the presence of complex lesions (HR: 2.70; CI: 1.15-6.32), balloon diameter used <14 mm (HR: 3.76; CI: 1.48-9.55), and immediate residual gradient >10 mm Hg (HR: 4.30; CI: 1.96-9.47).
CONCLUSIONS:
Both bare and covered stent implantation for aortic coarctation is a safe and efficacious treatment. By using covered stent implantation the spectrum of patients treated has increased with lower rates of acute and late complications.
AuthorsGianfranco Butera, João Luiz Langer Manica, Davide Marini, Luciane Piazza, Massimo Chessa, Raul Ivo Rossi Filho, Rogério E Sarmento Leite, Mario Carminati
JournalCatheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions (Catheter Cardiovasc Interv) Vol. 83 Issue 6 Pg. 953-63 (May 01 2014) ISSN: 1522-726X [Electronic] United States
PMID24459104 (Publication Type: Journal Article)
CopyrightCopyright © 2014 Wiley Periodicals, Inc.
Topics
  • Adolescent
  • Adult
  • Aged
  • Aortic Coarctation (diagnosis, therapy)
  • Aortography
  • Child
  • Child, Preschool
  • Endovascular Procedures (adverse effects, instrumentation)
  • Female
  • Humans
  • Italy
  • Male
  • Middle Aged
  • Prosthesis Design
  • Retreatment
  • Retrospective Studies
  • Risk Factors
  • Stents
  • Tertiary Care Centers
  • Time Factors
  • Treatment Outcome
  • Young Adult

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: