Abstract | OBJECTIVE: Previous studies have shown that lower serum amylase levels are associated with chronic pancreatitis. However, recently, lower serum amylase levels have been associated with metabolic syndrome (MS) and diabetes. The objective of the present study was to investigate the relationship between metabolic syndrome and diabetes and serum amylase levels in Chinese asymptomatic individuals living in Hangzhou, China. METHODS: RESULTS: Significant differences were found in sex, age, body mass index (BMI), systolic blood pressure, diastolic blood pressure, γ-GT, TG, HDL-C and FPG levels, as well as the prevalence of metabolic syndrome and diabetes among these four groups. Across Q1 to Q4, the prevalence of metabolic syndrome and diabetes decreased from 28.5-15.2% and 10.1-3.6%, respectively. Multiple logistic regression models following adjustment for age, gender, BMI, and γ-GT showed that the prevalence of metabolic syndrome (OR: 1.284; 95% CI: 0.909-1.813) and diabetes (OR: 2.081; 95% CI: 1.230-3.523) in the Q1 was significantly higher compared to the Q4. CONCLUSIONS: Low serum amylase levels are significantly associated with an increased prevalence of metabolic syndrome and diabetes in a Chinese asymptomatic population.
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Authors | Ying Zhao, Jie Zhang, Juanwen Zhang, Jianping Wu, Yu Chen |
Journal | Scandinavian journal of clinical and laboratory investigation
(Scand J Clin Lab Invest)
Vol. 74
Issue 3
Pg. 235-9
(Apr 2014)
ISSN: 1502-7686 [Electronic] England |
PMID | 24456421
(Publication Type: Journal Article)
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Chemical References |
- Apolipoproteins
- Biomarkers
- Blood Glucose
- Cholesterol, HDL
- Cholesterol, LDL
- Triglycerides
- C-Reactive Protein
- gamma-Glutamyltransferase
- Amylases
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Topics |
- Adult
- Aged
- Amylases
(blood)
- Apolipoproteins
(blood)
- Asymptomatic Diseases
- Biomarkers
(blood)
- Blood Glucose
(metabolism)
- C-Reactive Protein
(metabolism)
- China
(epidemiology)
- Cholesterol, HDL
(blood)
- Cholesterol, LDL
(blood)
- Diabetes Complications
- Diabetes Mellitus
(blood, epidemiology)
- Female
- Humans
- Logistic Models
- Male
- Metabolic Syndrome
(blood, complications, epidemiology)
- Middle Aged
- Prevalence
- Triglycerides
(blood)
- gamma-Glutamyltransferase
(blood)
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