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HLA-B39 and the axial type of psoriatic arthritis.

Abstract
The frequency distribution of HLA-B38 and HLA-B39 was studied in a group of 50 unrelated psoriatic arthritis patients. A high increase of HLA-B39 was noted in the subgroup with axial arthropathy. All B39 positive patients presented with spondylitis and/or sacroiliitis. The hypothesis is formulated that HLA-B39 may discriminate a genetic subset of psoriatic arthritis characterized by a particular susceptibility to develop axial involvement.
AuthorsE Crivellato, T Zacchi
JournalActa dermato-venereologica (Acta Derm Venereol) Vol. 67 Issue 3 Pg. 249-50 ( 1987) ISSN: 0001-5555 [Print] Sweden
PMID2442939 (Publication Type: Journal Article)
Chemical References
  • HLA Antigens
  • HLA-B Antigens
  • HLA-B38 Antigen
  • HLA-B39 Antigen
Topics
  • Arthritis (immunology)
  • Female
  • HLA Antigens (analysis)
  • HLA-B Antigens
  • HLA-B38 Antigen
  • HLA-B39 Antigen
  • Humans
  • Male
  • Psoriasis (immunology)
  • Sacroiliac Joint
  • Spondylitis (immunology)

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