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A novel method for increased yield of immunocompetent virus for vaccine production.

Abstract
Cultured human cells exposed to the pesticide emulsifier Atlox, 6 to 8 h prior to Infection with influenza A virus, increased virus production approximately 10-fold. Antibodies against the 'enhanced virus' neutralized plaque formation and reacted equally well with non-enhanced virus in serological tests (haemagglutination-inhibition and radioimmunoassays). The procedure has great potential in cutting costs of production for some virus vaccines.
AuthorsA A Qureshi
JournalWorld journal of microbiology & biotechnology (World J Microbiol Biotechnol) Vol. 7 Issue 5 Pg. 567-70 (Sep 1991) ISSN: 0959-3993 [Print] Germany
PMID24425199 (Publication Type: Journal Article)

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