HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Experimental transclival exposure and repair of the abducens nerve in cats.

Abstract
Operations were carried out on eight cats using a transcervical, transclival approach to expose the sixth cranial nerve just beside the basilar artery. In one case 5 mm of the nerve were resected; three months later no reinnervation was seen. In another cat the nerve ends were merely adapted, and good regeneration was seen despite slight neuroma formation. In a third case TabotampR and Aron-Alpha R were used to repair the skull base; this resulted in a neuroma and in atrophy of the sixth cranial nerve with scar adhesions rendering regeneration impossible. In five cases the transsected nerves were glued together with a fibrin adhesive, with excellent results: very good regeneration and reinnervation occurred within three months with ideal parallel alignment of the nerve fibres at the site of the lesion.
AuthorsG Sandvoss, G Stoltenburg-Didinger, M G Yasargil
JournalNeurochirurgia (Neurochirurgia (Stuttg)) Vol. 30 Issue 3 Pg. 65-8 (May 1987) ISSN: 0028-3819 [Print] Germany
PMID2441279 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
Chemical References
  • Drug Combinations
  • Fibrin Tissue Adhesive
  • Fibrinogen
  • Factor XIII
  • Aprotinin
  • Thrombin
Topics
  • Abducens Nerve (pathology, surgery)
  • Animals
  • Aprotinin (administration & dosage)
  • Cats
  • Cranial Fossa, Posterior
  • Drug Combinations (administration & dosage)
  • Factor XIII (administration & dosage)
  • Fibrin Tissue Adhesive
  • Fibrinogen (administration & dosage)
  • Microsurgery
  • Nerve Regeneration (drug effects)
  • Thrombin (administration & dosage)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: