Fibrosing mediastinitis mimicking sarcoidosis.

Abstract

Fibrosing mediastinitis (FM), also called sclerosing mediastinitis or mediastinal fibrosis, is a rare disease characterized by excessive fibrotic reaction in the mediastinum and may compromise the airway, the great vessels and other mediastinal structures, with a morbidity directly related to the location and extent of fibrosis. The cause is not always known but is often the result of a granulomatous disease, most often the histoplasmosis. We report a 43-year-old woman with a history of tuberculosis infection 23 years ago. She attended the pulmonology clinic for cough and dyspnea. Physical examination revealed jugular venous distention at 90°. In computed tomography scan of the chest with contrast (c/c), we observed a mediastinal nodal cast provoking cava compression and obliteration of main and intermediary right lobar bronchus. The pathological examination was FM.

• Authors: Marta Ferrer Galván, José Antonio Rodríguez Portal, María Pilar Serrano Gorarredona, Lourdes Gómez Izquierdo
• Journal: The clinical respiratory journal (Clin Respir J) Vol. 9 Issue 1 Pg. 125-8 (Jan 2015) ISSN: 1752-699X [Electronic] England
• PMID: 24405501 (Publication Type: Case Reports, Journal Article)
• Copyright: © 2014 John Wiley & Sons Ltd.

Topics

• Adult
• Diagnosis, Differential
• Female
• Humans
• Mediastinitis (complications, diagnosis, therapy)
• Sarcoidosis (diagnosis)
• Sclerosis (complications, diagnosis, therapy)