Metformin, oral contraceptives or both to manage oligo-amenorrhea in adolescents with polycystic ovary syndrome? A clinical review.

Abstract

The management of oligo-amenorrhea in adolescent patients with polycystic ovary syndrome (PCOS) represents an important and difficult challenge. Metformin and/or oral contraceptives (OCs) are different strategies widely proposed in these patients. The objective of the current review was to provide an overview on the use of metformin and/or OCs for the management of oligo-amenorrhea in adolescents with PCOS underlining their potential risks and benefits in order to help the clinician to choose the best patients' tailored treatment.

• Authors: Stefano Palomba, Caterina Materazzo, Angela Falbo, Francesco Orio, Giovanni Battista La Sala, Charles Sultan
• Journal: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology (Gynecol Endocrinol) Vol. 30 Issue 5 Pg. 335-40 (May 2014) ISSN: 1473-0766 [Electronic] England
• PMID: 24405081 (Publication Type: Journal Article, Review)

Chemical References

• Contraceptives, Oral
• Metformin

Topics

• Adolescent
• Amenorrhea (drug therapy)
• Contraceptives, Oral (therapeutic use)
• Female
• Humans
• Metformin (therapeutic use)
• Polycystic Ovary Syndrome (drug therapy)