[A case of Stage IV sigmoid colon cancer cured with radical combined modality therapy].

Abstract

The patient was a 54-year-old man who had undergone resection of the sigmoid colon for unresectable sigmoid colon cancer with multiple liver( H1), lymph node, and lung metastases at the previous hospital. Chemotherapy with 5-fuorouracil, Leucovorin, and oxaliplatin (mFOLFOX6) plus bevacizumab was initiated after surgery. The outcome was partial response. The patient was introduced to our hospital because he had relocated. Based on the findings of the patient's computed tomography( CT) and positron emission tomography( PET)-CT scans, we decided to perform radical resection. We performed partial hepatectomy( S7 and S8) and pancreatoduodenectomy for metastases to the hepatoduodenal ligament lymph node. After confirming that there was no recurrence, he underwent right partial pneumonectomy. Currently, the patient shows no signs of recurrence. The therapy for colon cancer should include aggressive radical surgery to control metastasis.

• Authors: Akihito Babaya, Mutsumi Fukunaga, Tameyoshi Yamamoto, Kazuyuki Oda, Ken Nakata, Hiroki Ohzato
• Journal: Gan to kagaku ryoho. Cancer & chemotherapy (Gan To Kagaku Ryoho) Vol. 40 Issue 12 Pg. 1956-8 (Nov 2013) ISSN: 0385-0684 [Print] Japan
• PMID: 24393978 (Publication Type: Case Reports, English Abstract, Journal Article, Review)

Chemical References

• Antibodies, Monoclonal, Humanized
• Organoplatinum Compounds
• Bevacizumab
• Leucovorin
• Fluorouracil

Topics

• Antibodies, Monoclonal, Humanized (administration & dosage)
• Antineoplastic Combined Chemotherapy Protocols (administration & dosage, therapeutic use)
• Bevacizumab
• Combined Modality Therapy
• Fluorouracil (administration & dosage)
• Humans
• Leucovorin (administration & dosage)
• Male
• Middle Aged
• Neoplasm Metastasis
• Neoplasm Staging
• Organoplatinum Compounds (administration & dosage)
• Sigmoid Neoplasms (drug therapy, pathology, surgery)