Failure of secondary prophylaxis with erythromycin in rheumatic heart disease.

Abstract

BACKGROUND:

Erythromycin is recommended for secondary prophylaxis in children with rheumatic heart disease, who are allergic to penicillin.

CASE CHARACTERISTICS:

A 9-year-old girl, with rheumatic heart disease, on secondary prophylaxis with erythromycin 250 mg BD, presented with acute rheumatic fever.

OUTCOME:

Responded to steroids and started on a higher dose (250 mg TDS) of erythromycin for secondary prophylaxis.

MESSAGE:

There is need to document the resistance of group A streptococci to erythromycin.

• Authors: Dinesh Kumar Yadav, Puneet Anand, Eden Bhutia
• Journal: Indian pediatrics (Indian Pediatr) Vol. 50 Issue 11 Pg. 1058-9 (Nov 08 2013) ISSN: 0974-7559 [Electronic] India
• PMID: 24382905 (Publication Type: Case Reports, Journal Article)

Chemical References

• Anti-Bacterial Agents
• Anti-Inflammatory Agents
• Erythromycin
• Prednisolone

Topics

• Anti-Bacterial Agents (therapeutic use)
• Anti-Inflammatory Agents (therapeutic use)
• Antibiotic Prophylaxis
• Child
• Erythromycin (therapeutic use)
• Female
• Humans
• Prednisolone (therapeutic use)
• Rheumatic Heart Disease (drug therapy)
• Treatment Failure