[A case of multiple myeloma responding very well to the combination of K18 with prednisolone].

Abstract

A case of multiple myeloma refractory to various anticancer drugs was effectively treated with the combination of K 18 with prednisolone, which led to a remarkable decrease of serum M-protein and overall recovery. In 8 months of the treatment, although slight bone marrow suppression was noted, no severe side effect was observed. The patient has survived for more than one year in remission. We suggest that the combination of K18 with prednisolone may be effective for multiple myeloma which is unresponsive to treatment with anticancer drugs.

• Authors: C Ishioka, R Kanamaru, T Sato, Y Konishi, T Himori, Y Mimata, A Wakui
• Journal: Gan to kagaku ryoho. Cancer & chemotherapy (Gan To Kagaku Ryoho) Vol. 14 Issue 4 Pg. 1164-6 (Apr 1987) ISSN: 0385-0684 [Print] Japan
• PMID: 2436580 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Drug Combinations
• Immunotoxins
• K-18 conjugate
• gamma-Globulins
• Prednisolone
• Melphalan

Topics

• Drug Combinations (administration & dosage, therapeutic use)
• Drug Therapy, Combination
• Female
• Humans
• Immunotoxins
• Melphalan (administration & dosage, therapeutic use)
• Middle Aged
• Multiple Myeloma (therapy)
• Prednisolone (administration & dosage, therapeutic use)
• Remission Induction
• gamma-Globulins (administration & dosage, therapeutic use)