Abstract | STUDY DESIGN: Randomised, controlled, single-blind, three-arm parallel-group trial set in general dental practice with a single general dental practitioner operator/assessor. INTERVENTION: Seventy-five adult patients, with basic periodontal examination scores of 0 in all sextants, good oral hygiene, at least one sensitive tooth (not diagnosed as pulpitis) and willing to comply with the trial regime were entered into the trial and randomised. Seventy-two participants completed the study. The three interventions were; non-desensitising toothpaste (Colgate Cavity Protection Regular, Colgate-Palmolive, USA), desensitising toothpaste ( Colgate Sensitive Fresh Stripe, Colgate-Palmolive, USA) and dentine bonding agent (Seal and Protect, Denpsly, USA). The non-desensitising toothpaste and desensitising toothpastes were provided to the subjects for use at home but dentine bonding agent was applied in the surgery. OUTCOME MEASURE: Dentinal hypersensitivity was measured using a participant completed Visual Analogue Scale (VAS) at baseline, two weeks, three months and six months. At baseline and six months a standardised air blast to the buccal cervical root stimulus was used with the VAS. At two weeks and at three months participants self-completed the VAS at home with no stimulus. RESULTS: Although there was a reduction in dentinal hypersensitivity over time for all three groups, dentinal hypersensitivity reduced significantly (p<0.0001) in both desensitising toothpaste and dentine bonding agent groups. The mean VAS scores in the dentine bonding agent group were statistically significantly lower when compared to both non-desensitising toothpaste (p<0.001) and desensitising toothpaste (p<0.001). In addition, mean scores for non-desensitising toothpaste were higher than desensitising toothpaste (p<0.05). CONCLUSIONS: Dentine bonding agents provided the greatest improvement in dentinal hypersensitivity at two weeks and six months. This reduction was greater than that achieved with the desensitising and non-desensitising toothpastes tested.
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Authors | Thomas Lamont, Nicola Innes |
Journal | Evidence-based dentistry
(Evid Based Dent)
Vol. 14
Issue 4
Pg. 105-6
(Dec 2013)
ISSN: 1476-5446 [Electronic] England |
PMID | 24357819
(Publication Type: Journal Article, Comment)
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Chemical References |
- Dentin Desensitizing Agents
- Dentin-Bonding Agents
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Topics |
- Dentin Desensitizing Agents
(therapeutic use)
- Dentin Sensitivity
(prevention & control)
- Dentin-Bonding Agents
(therapeutic use)
- Female
- Humans
- Male
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