Comparison of tolerability and adverse events following treatment with two GnRH agonists in patients with advanced prostate cancer.

This multicenter, randomized, crossover, open-label study (ClinicalTrials.gov identifier: NCT01161563) assessed patients'and clinicians'perceptions of injection site tolerability and adverse events following the intramuscular injection of triptorelin pamoate or subcutaneous injection of leuprolide acetate in 107 male, patients with advanced prostate cancer.
AuthorsNeal D Shore, Paul Sieber, Leanne Schimke, Adam Perzin, Scott Olsen
JournalUrologic nursing (Urol Nurs) 2013 Sep-Oct Vol. 33 Issue 5 Pg. 236-44, 248 ISSN: 1053-816X [Print] United States
PMID24354113 (Publication Type: Comparative Study, Journal Article, Multicenter Study, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)
Chemical References
  • Antineoplastic Agents, Hormonal
  • Gonadotropin-Releasing Hormone
  • Triptorelin Pamoate
  • Leuprolide
  • Aged
  • Aged, 80 and over
  • Antineoplastic Agents, Hormonal (administration & dosage, adverse effects)
  • Cross-Over Studies
  • Gonadotropin-Releasing Hormone (agonists)
  • Humans
  • Leuprolide (administration & dosage, adverse effects)
  • Male
  • Middle Aged
  • Prostatic Neoplasms (drug therapy, nursing)
  • Triptorelin Pamoate (administration & dosage, adverse effects)

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