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Failure of malaria chemoprophylaxis with mefloquine in an oversize traveller to Mozambique.

Abstract
A case of failure of mefloquine prophylaxis in an oversize traveller, who correctly took the drug. This case seems to be attributed to mefloquine resistance, however it is suggested that mefloquine dosage should be modulated by body weight, as is already indicated by some authorities.
AuthorsFederico Gobbi, Andrea Rossanese, Dora Buonfrate, Andrea Angheben, Gianluigi Lunardi, Zeno Bisoffi
JournalMalaria journal (Malar J) Vol. 12 Pg. 451 (Dec 18 2013) ISSN: 1475-2875 [Electronic] England
PMID24350652 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Antimalarials
  • Mefloquine
Topics
  • Antimalarials (therapeutic use)
  • Chemoprevention (methods)
  • Drug Resistance
  • Humans
  • Malaria (prevention & control)
  • Male
  • Mefloquine (therapeutic use)
  • Middle Aged
  • Mozambique
  • Plasmodium falciparum (drug effects, isolation & purification)
  • Travel
  • Treatment Failure

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