Post-
steroid panniculitis (PSP) is a rare clinical entity which presents after rapid withdrawal of high doses of systemic
corticosteroids. As few as 20 cases have been reported in literature till now. Here, we report a case of post-
steroid panniculitis occurring in a 9-year-old boy after rapid tapering and discontinuation of
corticosteroids administered for the treatment of
nephrotic syndrome. He presented with multiple erythematous painful indurated nodules over the face, arms, forearms, thighs, and legs. Histopathologic examination of the nodule revealed lobular
panniculitis with lymphocytes, neutrophils, and multiple multinucleated giant cells. It also showed multiple needle-shaped clefts. Based on history, clinical features, and histopathologic findings, a diagnosis of post-
steroid panniculitis was made and the patient was restarted on systemic
corticosteroids. The lesions resolved in 4 weeks. We report this case to highlight the importance of gradual tapering of
corticosteroids.