Treatment of recalcitrant facial verrucae vulgares with sinecatechins (greentea catechins) ointment.

Abstract

BACKGROUND:

Facial verrucae vulgares are benign, but disfiguring skin manifestations of human papilloma virus infection. They are found as verrucae planae juveniles in young adults, but also as common warts in immunocompromised or atopic patients.

OBJECTIVE:

To find an alternative, non-surgical treatment for a young man with atopic dermatitis and facial warts, who had not responded to 5-FU ointment, waterfiltered infrared A (wIRA) irradiation and topical retinoids.

METHODS:

Topical treatment with a sinecatechins 10% ointment (Veregen(TM) ) as approved for genital warts thrice daily for 3 weeks in a 34-year-old man with atopic dermatitis

RESULTS:

Complete remission of all facial warts was achieved within 20 days. Few side-effects were observed (initially some light skin irritation only).

CONCLUSION:

In this case, topical sinecatechins proved to be a well-tolerated and effective alternative to treat recalcitrant facial warts without surgery.

• Authors: A Clouth, H Schöfer
• Journal: Journal of the European Academy of Dermatology and Venereology : JEADV (J Eur Acad Dermatol Venereol) Vol. 29 Issue 1 Pg. 178-9 (Jan 2015) ISSN: 1468-3083 [Electronic] England
• PMID: 24341392 (Publication Type: Case Reports, Journal Article)
• Copyright: © 2013 European Academy of Dermatology and Venereology.

Chemical References

• Ointments
• Plant Extracts
• green tea extract polyphenone E
• Catechin

Topics

• Adult
• Camellia sinensis
• Catechin (analogs & derivatives, therapeutic use)
• Facial Dermatoses (drug therapy, virology)
• Humans
• Male
• Ointments (therapeutic use)
• Phytotherapy
• Plant Extracts (therapeutic use)
• Retreatment
• Warts (drug therapy)