[Opportunities of correction of rheological properties of blood in intensive therapy in patients with peritonitis and acute bowel obstruction].

Abstract

An analysis of efficacy of 1.5% reamberin solution usage was made in 80 patients for correction of blood rheological properties disorder in the case of peritonitis and bowel obstruction. It was established, that reamberin, which was administered in the dose of 500 ml after 12 hours of the beginning of intensive care during 48 hours, efficiently corrected the rheological disorders. It was because the erythron and reticulocyte production were activated, the hyposmolarity was removed, the intensity of free radical oxidation and peroxide oxidation of lipids was decreased and the antioxidant status was restored. This facilitated the hydrophily and erythrocyte volume decrease, the haemolysis reduction and qualitative gas exchange at the level of tissues.

• Authors: Iu P Orlov, V N Lukach, G V Chekmarev, A V Glushchenko, S B Zhitenev
• Journal: Vestnik khirurgii imeni I. I. Grekova (Vestn Khir Im I I Grek) Vol. 172 Issue 4 Pg. 17-22 ( 2013) ISSN: 0042-4625 [Print] Russia (Federation)
• PMID: 24341240 (Publication Type: Comparative Study, English Abstract, Journal Article)

Chemical References

• Anti-Bacterial Agents
• Reamberin
• Succinates
• Meglumine

Topics

• Acute Disease
• Anti-Bacterial Agents (therapeutic use)
• Blood Viscosity
• Critical Care (methods)
• Follow-Up Studies
• Humans
• Intestinal Obstruction (blood, complications, therapy)
• Meglumine (analogs & derivatives, therapeutic use)
• Middle Aged
• Peritonitis (blood, etiology, therapy)
• Succinates (therapeutic use)
• Treatment Outcome