Efficacy of short-term postoperative perfluoro-n-octane tamponade for pediatric complex retinal detachment.

Abstract

PURPOSE:

To evaluate the efficacy of perfluoro-n-octane as a postoperative short-term tamponade after vitrectomy in pediatric cases with complex retinal detachment (RD) and proliferative vitreoretinopathy (PVR).

DESIGN:

Prospective, noncomparative, interventional case series.

METHODS:

The medical records of 10 eyes of 9 children (6 boys and 3 girls), whose age ranged from 3 months to 11 years, with a median of 7.5 months, were reviewed. The cause of the PVR was retinopathy of prematurity (7 eyes of 6 patients); familial exudative vitreoretinopathy; or tractional RD associated with congenital optic nerve anomalies,(1) and persistent fetal vasculature. Perfluoro-n-octane was injected into the eyes at the primary surgery in 2 eyes and at the repeat surgeries in 8 eyes. The perfluoro-n-octane was removed after 1 to 4 postoperative weeks. The patients were followed for 5 to 43 months.

RESULTS:

At the last examination, the retinas were reattached in 8 eyes (80%). In the other two eyes, a retinal attachment was not obtained. Postoperatively, the best-corrected visual acuity improved from hand motion to 0.1 in 1 eye and could not be measured in the other 9 patients because of their ages. No apparent adverse events related to the use of perfluoro-n-octane were noted.

CONCLUSIONS:

Although cautions should be exercised regarding potential mechanical retinal injuries by heavy liquids in the eye, short-term perfluoro-n-octane tamponade was effective in pediatric cases with severe PVR in which retinal reattachment is considered to be difficult with conventional gas or silicone oil tamponade.

• Authors: Ayako Imaizumi, Shunji Kusaka, Hiroe Noguchi, Yoshikazu Shimomura, Shoichi Sawaguchi
• Journal: American journal of ophthalmology (Am J Ophthalmol) Vol. 157 Issue 2 Pg. 384-389.e2 (Feb 2014) ISSN: 1879-1891 [Electronic] United States
• PMID: 24332376 (Publication Type: Case Reports, Journal Article, Multicenter Study, Research Support, Non-U.S. Gov't)
• Copyright: Copyright © 2014 Elsevier Inc. All rights reserved.

Chemical References

• Fluorocarbons
• perfluorooctane

Topics

• Child
• Drainage
• Endotamponade
• Female
• Fluorocarbons (therapeutic use)
• Humans
• Infant
• Male
• Postoperative Care
• Prospective Studies
• Retina (physiopathology)
• Retinal Detachment (physiopathology, surgery)
• Treatment Outcome
• Visual Acuity (physiology)
• Vitrectomy
• Vitreoretinopathy, Proliferative (physiopathology, surgery)