Abstract | BACKGROUND: METHODS:
Dyspepsia was assessed through the Porto Alegre Dyspeptic Symptoms Questionnaire (PADYQ). PADYQ's scores ≥ 6 classified participants as dyspeptic. The octanoic acid breath test using ¹³carbon was employed to assess the gastric emptying time. Based on the test, time in minutes to metabolize the first half of the ¹³carbon in the test meal (t1/2) was calculated. Association of dyspepsia with gastric emptying time was tested by the correlation between PADYQ scores and t1/2, and also by comparing t1/2 between dyspeptics and non-dyspeptics. RESULTS: There were 34 (68.0%) dyspeptic patients. Dyspepsia score was positively correlated with t1/2 (r = 0.366; p = 0.009). Dyspeptics had longer t1/2 compared to non-dyspeptics, respectively, 238.0 ± 92.9 versus 185.5 ± 45.5 minutes (p = 0.042). CONCLUSIONS: Delayed gastric emptying was associated with dyspepsia. Prokinetic medications could have a role in preventing or relieving dyspeptic symptoms among HD patients. Future research in larger samples is necessary to confirm this association.
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Authors | Luiz Derwal Salles Junior, Paulo Roberto Santos, Armênio Aguiar dos Santos, Marcellus Henrique Loiola Ponte de Souza |
Journal | BMC nephrology
(BMC Nephrol)
Vol. 14
Pg. 275
(Dec 14 2013)
ISSN: 1471-2369 [Electronic] England |
PMID | 24330675
(Publication Type: Journal Article, Randomized Controlled Trial)
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Topics |
- Adult
- Dyspepsia
(diagnosis, etiology, physiopathology)
- Female
- Gastric Emptying
- Humans
- Kidney Failure, Chronic
(complications, physiopathology, rehabilitation)
- Male
- Middle Aged
- Renal Dialysis
- Reproducibility of Results
- Sensitivity and Specificity
- Treatment Outcome
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