Abstract | BACKGROUND AND PURPOSE: EXPERIMENTAL APPROACH: KEY RESULTS: CONCLUSIONS AND IMPLICATIONS:
Imidazoline I2 receptor ligands have antihyperalgesic effects in rat models of inflammatory and neuropathic pain and may represent a new class of pharmacotherapeutics for the management of chronic pain.
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Authors | Jun-Xu Li, David A Thorn, Yanyan Qiu, Bi-Wen Peng, Yanan Zhang |
Journal | British journal of pharmacology
(Br J Pharmacol)
Vol. 171
Issue 6
Pg. 1580-90
(Mar 2014)
ISSN: 1476-5381 [Electronic] England |
PMID | 24329196
(Publication Type: Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't)
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Copyright | © 2013 The British Pharmacological Society. |
Chemical References |
- Imidazoline Receptors
- Ligands
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Topics |
- Animals
- Disease Models, Animal
- Imidazoline Receptors
(metabolism)
- Inflammation
(drug therapy, metabolism)
- Ligands
- Male
- Pain
(drug therapy, metabolism)
- Peripheral Nervous System Diseases
(drug therapy, metabolism)
- Rats
- Rats, Sprague-Dawley
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