Evaluation of propofol as a general anesthetic agent for minor oral surgical procedure.

Abstract

Nausea and vomiting following anesthesia is a distressing problem for the patient as it increases the recovery time, intensity of nursing care and delays discharge. The aim of randomized controlled single blind study is to evaluate the efficacy and safety of subhypnotic doses of propofol for the prevention of postoperative nausea and vomiting (PONV) in day care management of cases in oral and maxillofacial surgeries. Twenty-five patient of ASA-1 with age ranging from 12 to 40 years were scheduled for various maxillofacial surgical cases like fracture, cyst enucleation, surgical removal of 3rd molar, etc. were given propofol at the dose of 2 to 2.5 mg/kg as induction dose and sedation was maintained with the dose 5 to 10 mg/min. There was no significant effect on heart rate, systolic and diastolic blood pressure, respiratory rate and oxygen saturation intraoperatively. In conclusion, a subhypnotic dose of propofol is fast acting, safe and easily controllable, short acting general anesthetic agent with rapid recovery. The study found that the PONV was significantly reduced in the patient with propofol, no hemodynamic derangements were noted in the postoperative period.

• Authors: Nitin Jaggi, Amit Kalra, Gunpreet Kaur Baghla, Sonali V Medsinge, Nikhil Purohit
• Journal: The journal of contemporary dental practice (J Contemp Dent Pract) Vol. 14 Issue 4 Pg. 605-9 (Jul 01 2013) ISSN: 1526-3711 [Electronic] India
• PMID: 24309336 (Publication Type: Comparative Study, Journal Article, Randomized Controlled Trial)

Chemical References

• Anesthetics, Intravenous
• Antiemetics
• Oxygen
• Propofol

Topics

• Adolescent
• Adult
• Ambulatory Surgical Procedures (methods)
• Anesthesia Recovery Period
• Anesthesia, Dental (methods)
• Anesthetics, Intravenous (administration & dosage)
• Antiemetics (therapeutic use)
• Blood Pressure (drug effects)
• Child
• Conscious Sedation (methods)
• Dental Anxiety (prevention & control)
• Heart Rate (drug effects)
• Humans
• Minor Surgical Procedures (methods)
• Monitoring, Intraoperative
• Oral Surgical Procedures (methods)
• Oxygen (blood)
• Postoperative Nausea and Vomiting (prevention & control)
• Propofol (administration & dosage, therapeutic use)
• Respiration (drug effects)
• Safety
• Single-Blind Method
• Treatment Outcome
• Young Adult