Abstract |
Primary myelofibrosis (PMF) is a myeloproliferative neoplasm frequently complicated by transfusion dependent anemia. Both anemia and transfusion-dependence are associated with a poor outcome, at least in part because of toxic effects of iron overload (IOL). Iron-chelating therapy (ICT) is increasingly used in order to prevent IOL in this setting. Here, we describe the case of a 73-year-old man affected by PMF and severe transfusion-dependent anemia who experienced a dramatic erythroid response after being treated with deferasirox to prevent IOL.
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Authors | Del Corso Lisette, Balleari Enrico, Arboscello Eleonora, Ghio Riccardo, Mencoboni Manlio, Racchi Omar |
Journal | Case reports in hematology
(Case Rep Hematol)
Vol. 2013
Pg. 520712
( 2013)
ISSN: 2090-6560 [Print] United States |
PMID | 24307957
(Publication Type: Journal Article)
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