Abstract | OBJECTS: METHODS:
Antibiotic elution and concentration of gentamcin and vancomycin were measured using photometrically-based measurement and homogeneous particle-enhanced turbidimetric inhibition immunoassays (PETINIA). RESULTS: Initially both materials showed a high release of the loaded antibiotics, with Cerasorb M(®) showing lower release levels for gentamicin and vancomycin than Cerasorb(®). Gentamicin concentrations of Cerasorb M granules and Cerasorb were below the minimum detectiontreshold until day four and six of the experiment respectively. The vancomycin release-level followed a similar pattern, although the vancomycin concentration eluted by Cerasorb M(®) granules stayed above the detection threshold during the experimental time. CONCLUSIONS:
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Authors | Gerrit Steffen Maier, Klaus Edgar Roth, Stefan Andereya, Klaus Birnbaum, Christopher Niedhart, Markus Lühmann, Jörg Ohnsorge, Uwe Maus |
Journal | The open orthopaedics journal
(Open Orthop J)
Vol. 7
Pg. 624-9
( 2013)
ISSN: 1874-3250 [Print] United Arab Emirates |
PMID | 24285988
(Publication Type: Journal Article)
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