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Multifunctional polypyrrole@Fe(3)O(4) nanoparticles for dual-modal imaging and in vivo photothermal cancer therapy.

Abstract
Magnetic Fe3 O4 crystals are produced in situ on preformed polypyrrole (PPY) nanoparticles by rationally converting the residual Fe species in the synthetic system. The obtained PPY@Fe(3)O(4)composite nanoparticles exhibit good photostability and biocompatibility, and they can be used as multifunctional probes for MRI, thermal imaging, and photothermal ablation of cancer cells.
AuthorsQiwei Tian, Qian Wang, Ke Xin Yao, Baiyang Teng, Jizhe Zhang, Shiping Yang, Yu Han
JournalSmall (Weinheim an der Bergstrasse, Germany) (Small) Vol. 10 Issue 6 Pg. 1063-8 (Mar 26 2014) ISSN: 1613-6829 [Electronic] Germany
PMID24285365 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
Copyright© 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Chemical References
  • Ferric Compounds
  • Polymers
  • Pyrroles
  • ferric oxide
  • polypyrrole
Topics
  • Animals
  • Ferric Compounds (chemistry)
  • HeLa Cells
  • Humans
  • Hyperthermia, Induced (methods)
  • Magnetic Resonance Imaging
  • Mice
  • Mice, Nude
  • Multimodal Imaging
  • Nanoparticles (chemistry, ultrastructure)
  • Neoplasms (therapy)
  • Phototherapy (methods)
  • Polymers (chemistry)
  • Pyrroles (chemistry)
  • Spectrophotometry, Ultraviolet
  • Temperature

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