Abstract | BACKGROUND: METHODS: Patients with frozen shoulder who presented with pain as the symptom were divided at random into a celecoxib treatment group (100 mg/dose, twice daily; n = 37) and a loxoprofen treatment group (60 mg/dose, 3 times daily; n = 33). Medication was continued for 1-2 weeks in each group. RESULTS: Each patient was asked to rate the pain on a visual analog scale (score 0-5). This score significantly improved (indicating marked alleviation of pain) in both the celecoxib group (from 3.41 ± 0.86 before treatment to 2.30 ± 1.02 after treatment) and the loxoprofen group (from 3.73 ± 0.67 before treatment to 2.76 ± 0.96 after treatment). In the analysis of disappearance of pain, the percentage of patients showing disappearance of nocturnal pain was significantly higher in the celecoxib group (71.4 %) than in the loxoprofen group (36.8 %). CONCLUSIONS:
|
Authors | Satoru Ohta, Osamu Komai, Hiroyoshi Hanakawa |
Journal | Modern rheumatology
(Mod Rheumatol)
Vol. 24
Issue 1
Pg. 144-9
(Jan 2014)
ISSN: 1439-7609 [Electronic] England |
PMID | 24261771
(Publication Type: Comparative Study, Journal Article, Randomized Controlled Trial)
|
Chemical References |
- Anti-Inflammatory Agents, Non-Steroidal
- Cyclooxygenase 2 Inhibitors
- Phenylpropionates
- Pyrazoles
- Sulfonamides
- loxoprofen
- Celecoxib
|
Topics |
- Adult
- Aged
- Aged, 80 and over
- Anti-Inflammatory Agents, Non-Steroidal
(therapeutic use)
- Bursitis
(drug therapy)
- Celecoxib
- Cyclooxygenase 2 Inhibitors
(therapeutic use)
- Female
- Humans
- Male
- Middle Aged
- Pain Measurement
- Phenylpropionates
(therapeutic use)
- Pyrazoles
(therapeutic use)
- Sulfonamides
(therapeutic use)
- Treatment Outcome
|