Neutrophilic eccrine hidradenitis associated with Hodgkin's disease and chemotherapy. A case report.

Abstract

A 44-year-old man with Hodgkin's disease developed fever and erythematous macules and plaques associated with doxorubicin, bleomycin, vinblastine, and dacarbazine chemotherapy. Biopsy results demonstrated a neutrophilic infiltrate around sweat glands and degeneration of eccrine glands. These findings are characteristic of neutrophilic eccrine hidradenitis, which, to our knowledge, has previously been reported only in patients with acute myelogenous leukemia who were receiving cytarabine chemotherapy. Neutrophilic eccrine hidradenitis may represent a reaction pattern to chemotherapeutic agents and may not be specific for a particular disease or drug.

• Authors: K R Beutner, C H Packman, W Markowitch
• Journal: Archives of dermatology (Arch Dermatol) Vol. 122 Issue 7 Pg. 809-11 (Jul 1986) ISSN: 0003-987X [Print] United States
• PMID: 2425751 (Publication Type: Case Reports, Journal Article)

Chemical References

• Bleomycin
• Vinblastine
• Dacarbazine
• Doxorubicin

Topics

• Adult
• Antineoplastic Combined Chemotherapy Protocols (adverse effects)
• Bleomycin (administration & dosage)
• Dacarbazine (administration & dosage)
• Doxorubicin (administration & dosage)
• Hodgkin Disease (complications)
• Humans
• Inflammation (etiology, pathology)
• Male
• Neutrophils (pathology)
• Sweat Gland Diseases (etiology, pathology)
• Sweat Glands (pathology)
• Vinblastine (administration & dosage)