Resolution of "salt and pepper" appearance of the skull with vitamin D therapy.

Abstract

Chronic hypovitaminosis D leads to state of decreased mineralization and generalized osteomalacia. It also results in secondary hyperparathyroidism causing increased bone turn over and decreased bone mass, manifested radiologically as a "salt and pepper" appearance in skull, subperiosteal resorption, bone cysts and lytic lesions. In this case, a young male patient with hypovitaminosis D and secondary hyperparathyroidism, radiological features show resolution of "salt and pepper" appearance of the skull with vitamin D in 11 months and regression of other lytic lesions.

• Authors: Gursimran Kaur, Parminder Singh, Naveen Mittal, Mani Kant Singla
• Journal: Indian journal of endocrinology and metabolism (Indian J Endocrinol Metab) Vol. 17 Issue Suppl 1 Pg. S194-7 (Oct 2013) ISSN: 2230-8210 [Print] India
• PMID: 24251156 (Publication Type: Case Reports)