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Evaluation of split renal function before and after renal arterial embolization for angiomyolipoma using absolute ethanol.

AbstractPURPOSE:
Transcatheter arterial embolization (TAE) with absolute ethanol is widely accepted as a therapeutic procedure for renal angiomyolipoma (AML). We aim to evaluate the split renal function before and after AE for renal AML by using 99m-technetium (99mTc)-mercaptoacetyltriglycine 3 (MAG3) renography.
METHODS:
This study was approved by the Institutional Review Board. The study population comprised 11 renal AML patients (three males, eight females, age 55.1 ± 13.8 years, AML in eight right and three left kidneys) who received unilateral renal TAE with absolute ethanol from April 2002 to January 2013. Blood renal function (i.e. serum creatinine and estimated glomerular filtration rate [eGFR] and split effective renal plasma flow [ERPF]) calculated on 99mTc-MAG3 renography was compared before and within 1 week after renal AE. Statistical analysis was calculated using Wilcoxon signed-ranked test.
RESULTS:
TAE for renal AML was technically successful in all patients. Serum creatinine and eGFR did not change before and after TAE. ERPF on the embolized kidney did not change before (127.3 ± 60.8 ml/min) and after (127.6 ± 47.4 ml/min) TAE (p = 0.9726). ERPF on the nonembolized kidney showed a statistically significant increase before (152.5 ± 46.8 ml/min) and within 1 week after (169.1 ± 41.5 ml/min) TAE (p = 0.0093 and p < 0.05, respectively).
CONCLUSION:
TAE for renal AML may not induce renal dysfunction on the embolized kidney and may immediately increase the renal blood flow of the nonembolized kidney.
AuthorsYasutaka Baba, Sadao Hayashi, Shunichiro Ikeda, Megumi Jinguji, Masatoyo Nakajo, Masayuki Nakajo
JournalCardiovascular and interventional radiology (Cardiovasc Intervent Radiol) Vol. 37 Issue 5 Pg. 1220-5 (Oct 2014) ISSN: 1432-086X [Electronic] United States
PMID24232038 (Publication Type: Journal Article)
Chemical References
  • Radiopharmaceuticals
  • Solvents
  • Technetium Tc 99m Mertiatide
  • Ethanol
Topics
  • Adult
  • Aged
  • Angiomyolipoma (therapy)
  • Embolization, Therapeutic (methods)
  • Ethanol (therapeutic use)
  • Female
  • Humans
  • Kidney (diagnostic imaging, physiopathology)
  • Kidney Function Tests (methods)
  • Kidney Neoplasms (therapy)
  • Male
  • Middle Aged
  • Radionuclide Imaging
  • Radiopharmaceuticals
  • Retrospective Studies
  • Solvents (therapeutic use)
  • Technetium Tc 99m Mertiatide
  • Treatment Outcome

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