[A case of liver metastasis of primary duodenal cancer effectively treated with docetaxel therapy].

Abstract

A 75-year-old man who complained of upper abdominal discomfort was diagnosed with primary duodenal cancer. The patient was treated with a pancreaticoduodenectomy, ascending colectomy and postoperative chemotherapy of S-1 and irinotecan[IRIS; S-1, 80mg/m2(days 1-14); irinotecan, 100 mg/m2(days 1 and 15, every 4 weeks)]. However, after 4 IRIS cycles, computed tomography revealed a liver metastasis and massive ascites. The patient received second-line chemotherapy of tri-weekly docetaxel[60mg/m2,(day 1, every 3 weeks)]. After 2 cycles of docetaxel therapy, the liver tumor and ascites became undetectable. The patient was doing well 13 months after the operation.

• Authors: Akiho Okada, Masahiro Hata, Yoshinori Taeda, Ryo Ushijima
• Journal: Gan to kagaku ryoho. Cancer & chemotherapy (Gan To Kagaku Ryoho) Vol. 40 Issue 11 Pg. 1541-4 (Nov 2013) ISSN: 0385-0684 [Print] Japan
• PMID: 24231711 (Publication Type: Case Reports, Journal Article, Review)

Chemical References

• Antineoplastic Agents
• Taxoids
• Docetaxel

Topics

• Aged
• Antineoplastic Agents (therapeutic use)
• Ascites (etiology)
• Docetaxel
• Duodenal Neoplasms (drug therapy, pathology, surgery)
• Humans
• Liver Neoplasms (drug therapy, secondary)
• Male
• Taxoids (therapeutic use)