[Radiosensitizing effect of interferon synthesis inducers].

Abstract	The preinjection of inductors of leukocytic interferon synthesis of rapid (poly I.poly C, dextransulfate) and slow (tyloron) types to mice bearing inoculated solid sarcoma 37 considerably increases the efficiency of X-irradiation of tumors: the coefficient of tumor growth inhibition (kappa *) exceeds 1.0, and the number of animals with the completely regressed tumors increases. The effectiveness of the procedure depends on the time of the injection of the preparations and modes of irradiation.
Authors	D L Leonidze, G G Afanas'ev, A M Poverennyĭ, I I Pelevina
Journal	Radiobiologiia (Radiobiologiia) 1986 Mar-Apr Vol. 26 Issue 2 Pg. 227-31 ISSN: 0033-8192 [Print] Russia (Federation)
Vernacular Title	Radiosensibiliziruiushchee deĭstvie induktorov sinteza interferona.
PMID	2422676 (Publication Type: Journal Article)
Chemical References	Dextrans Interferon Inducers Radiation-Sensitizing Agents Dextran Sulfate Tilorone Poly I-C
Topics	Animals Dextran Sulfate Dextrans (therapeutic use) Interferon Inducers (therapeutic use) Mice Mice, Inbred Strains Poly I-C (therapeutic use) Radiation-Sensitizing Agents Sarcoma 37 (radiotherapy) Sarcoma, Experimental (radiotherapy) Tilorone (therapeutic use)

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