Abstract | OBJECTIVES: METHODS: Thirty patients met the criteria for study inclusion and were treated with unsedated office-based injection laryngoplasty of Juvederm Ultra Plus gel over a 20-month period. The preinjection acoustic and aerodynamic measures, Voice Handicap Index, Glottal Function Index, and Dysphonia Severity Index were compared with values recorded at 1 and 4 months after injection. RESULTS: Data for 27 patients were available for follow-up analysis at 1 month, and 12 patients' data were available at 4 months. Significant improvements, compared to preinjection levels (p < 0.02), were shown in all outcome measures at 1 and 4 months. One patient required intravenous steroid therapy for delayed glottic inflammation that resolved without permanent sequelae. CONCLUSIONS: The injection of Juvederm Ultra Plus gel is a relatively safe procedure that allows for short-term improvements in objective and subjective outcome measures of vocal function in patients with glottic insufficiency, provided the surgeon remains alert to the possibility of postprocedural injection site inflammation.
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Authors | David C Upton, Matthew Johnson, Sherri K Zelazny, Seth H Dailey |
Journal | The Annals of otology, rhinology, and laryngology
(Ann Otol Rhinol Laryngol)
Vol. 122
Issue 9
Pg. 541-6
(Sep 2013)
ISSN: 0003-4894 [Print] United States |
PMID | 24224395
(Publication Type: Comparative Study, Journal Article)
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Chemical References |
- Gels
- Juvederm Ultra Plus
- Viscosupplements
- Hyaluronic Acid
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Topics |
- Adult
- Aged
- Aged, 80 and over
- Female
- Follow-Up Studies
- Gels
- Glottis
- Humans
- Hyaluronic Acid
(administration & dosage, therapeutic use)
- Injections
- Laryngoplasty
(methods)
- Laryngoscopy
- Male
- Middle Aged
- Patient Satisfaction
- Prospective Studies
- Stroboscopy
- Surveys and Questionnaires
- Time Factors
- Treatment Outcome
- Viscosupplements
(administration & dosage, therapeutic use)
- Vocal Cord Paralysis
(diagnosis, physiopathology, surgery)
- Voice Quality
(physiology)
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