Periocular photodynamic therapy for squamous intra-epidermal carcinoma.

Abstract

OBJECTIVES:

To evaluate the response of Metvix photodynamic therapy (PDT) for the treatment of periocular Bowen's disease.

METHODS:

Four patients with biopsy-proven Bowen' disease were treated with Metvix PDT between November 2010 and January 2012. A detailed description of the technique used is described.

RESULTS:

All of the patients tolerated the PDT well. All had some clinical response to the treatment, although there was not complete, lasting resolution beyond one year in three out of the four cases.

CONCLUSION:

PDT can be a good treatment in its own right in selected cases of periocular Bowen's disease.

• Authors: Natasha Casie Chetty, Bridget Hemmant, Anne-Marie Skellett
• Journal: The Journal of dermatological treatment (J Dermatolog Treat) Vol. 25 Issue 6 Pg. 516-8 (Dec 2014) ISSN: 1471-1753 [Electronic] England
• PMID: 24215518 (Publication Type: Journal Article)

Chemical References

• Photosensitizing Agents
• methyl 5-aminolevulinate
• Aminolevulinic Acid

Topics

• Aged
• Aged, 80 and over
• Aminolevulinic Acid (administration & dosage, analogs & derivatives)
• Biopsy
• Bowen's Disease (drug therapy)
• Eye
• Female
• Humans
• Male
• Photochemotherapy
• Photosensitizing Agents (administration & dosage)
• Skin Cream
• Skin Neoplasms (drug therapy)
• Treatment Outcome