Abstract | OBJECTIVE: DESIGN: RESULTS: Time × group interaction, group differences, and time effect on worst pain at each follow-up point were statistically significant (P < 0.05) among the groups. In the group receiving TENS and local injection of cobalamin and in the group receiving TENS with a combination of cobalamin and lidocaine, the mean ± SD pain scores were 4.0 ± 1.4 and 4.1 ± 1.2 at endpoint, 28 and 26 patients achieved pain reduction of 30% or greater, and 14 and 10 perceived worst pain of 3 or less, respectively. The activities of daily living and quality-of-life data at the study endpoint showed significant benefits in the group receiving TENS and local injection of cobalamin and in the group receiving TENS and a combination of cobalamin and lidocaine (P < 0.05). In the group receiving TENS and local injection of lidocaine, the mean ± SD pain score was 6.1 ± 1.2 at the endpoint relative to baseline (P < 0.05), and only six patients achieved pain reduction of 30% or greater. CONCLUSIONS:
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Authors | Gang Xu, Gang Xú, Yan Feng, Wei Zhen Tang, Zhong Wei Lv |
Journal | American journal of physical medicine & rehabilitation
(Am J Phys Med Rehabil)
Vol. 93
Issue 4
Pg. 287-98
(Apr 2014)
ISSN: 1537-7385 [Electronic] United States |
PMID | 24196971
(Publication Type: Journal Article, Randomized Controlled Trial)
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Chemical References |
- Anesthetics, Local
- Neuroprotective Agents
- Lidocaine
- Vitamin B 12
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Topics |
- Activities of Daily Living
- Aged
- Aged, 80 and over
- Anesthetics, Local
(therapeutic use)
- Combined Modality Therapy
- Drug Therapy, Combination
- Female
- Humans
- Injections, Subcutaneous
- Lidocaine
(therapeutic use)
- Male
- Middle Aged
- Neuralgia, Postherpetic
(therapy)
- Neuroprotective Agents
(therapeutic use)
- Quality of Life
- Transcutaneous Electric Nerve Stimulation
- Visual Analog Scale
- Vitamin B 12
(therapeutic use)
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