Abstract | PURPOSE: PATIENTS AND METHODS: A monocentric study was conducted retrospectively on patients receiving a radiotherapy or concurrent chemoradiotherapy for a head and neck cancer. A logistic model was performed in order to assess clinical or therapeutic risk factors for required artificial nutrition during treatment. Significant parameters, issued from multivariate analysis, were summed and weighted in a score aiming at estimating a malnutrition risk during radiotherapy. RESULTS: Among the 127 evaluated patients, 59 patients required artificial nutrition during radiotherapy. In multivariate analysis, predictive factors for malnutrition were weight loss superior to 5% in the 3 months before radiotherapy, advanced tumor stage (III-IV vs. I-II), and pain requiring strong analgesics (step II-III vs. I). Concurrent chemotherapy was identified as a significant risk factor also, but it was strongly correlated with the tumor stage. The score, estimated from these previous factors, allowed a prediction of a risk of enteral feeding with a sensitivity of 90% and a specificity of 85%. CONCLUSION:
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Authors | N Lescut, E Personeni, M Desmarets, M Puyraveau, R Hamlaoui, S Servagi-Vernat, J-F Bosset, F Nguyen |
Journal | Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique
(Cancer Radiother)
Vol. 17
Issue 7
Pg. 649-55
(Nov 2013)
ISSN: 1769-6658 [Electronic] France |
Vernacular Title | Évaluation d'un score prédictif de dénutrition chez les patients pris en charge par irradiation pour un cancer des voies aérodigestives supérieures : étude rétrospective chez 127 patients. |
PMID | 24183935
(Publication Type: English Abstract, Journal Article)
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Copyright | Copyright © 2013 Société française de radiothérapie oncologique (SFRO). Published by Elsevier SAS. All rights reserved. |
Chemical References |
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Topics |
- Adult
- Aged
- Aged, 80 and over
- Albuminuria
(epidemiology)
- Analgesics, Opioid
(therapeutic use)
- Chemoradiotherapy
- Female
- Gastrostomy
- Head and Neck Neoplasms
(pathology, therapy)
- Humans
- Logistic Models
- Male
- Malnutrition
(etiology, prevention & control)
- Middle Aged
- Neoplasm Staging
- Nutritional Support
- Pain
(drug therapy)
- Retrospective Studies
- Risk Assessment
- Risk Factors
- Weight Loss
- Young Adult
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