Sclerotherapy with polidocanol for treatment of aneurysmal bone cysts.

Abstract

BACKGROUND AND PURPOSE:

Recent data suggest that percutaneous sclerotherapy is a safe alternative to surgery for treatment of aneurysmal bone cysts (ABCs). We present our experience of this method.

METHODS:

We retrospectively analyzed data from 38 consecutive patients treated with repeated injections of polidocanol. Each injection consisted of 2-4 mg polidocanol per kg body weight. Radiological and clinical assessments were performed until healing.

RESULTS:

All cycts except 1 healed after a median of 4 (1-11) injections. A lesion failed to heal in 1 patient, who was operated. 3 patients experienced minor local inflammatory reactions.

INTERPRETATION:

Our results show that percutaneus sclerotherapy with polidocanol has high efficacy in the treatment of ABCs, with a low frequency of side effects. Our findings corroborate data presented in previous publications. We believe that the method will be especially valuable in ABCs of the pelvis and sacrum, where surgery is associated with considerable morbidity.

• Authors: Otte Brosjö, Pierre Pechon, Asle Hesla, Panagiotis Tsagozis, Henrik Bauer
• Journal: Acta orthopaedica (Acta Orthop) Vol. 84 Issue 5 Pg. 502-5 (Oct 2013) ISSN: 1745-3682 [Electronic] Sweden
• PMID: 24171682 (Publication Type: Journal Article)

Chemical References

• Sclerosing Solutions
• Polidocanol
• Polyethylene Glycols

Topics

• Adolescent
• Adult
• Bone Cysts, Aneurysmal (diagnostic imaging, therapy)
• Child
• Child, Preschool
• Female
• Humans
• Injections, Intralesional
• Male
• Musculoskeletal Pain (etiology)
• Polidocanol
• Polyethylene Glycols (administration & dosage)
• Radiography
• Retrospective Studies
• Sclerosing Solutions (administration & dosage)
• Treatment Outcome
• Young Adult