Abstract | PURPOSE: DATA SOURCES: CINAHL, Medline, Health Source: Nursing/Academic Edition, and Cochrane Library. CONCLUSIONS: Evidence from this review suggests that studies showed a significant relationship between statin intake and decreased serum levels of CoQ10. A few studies showed a benefit in symptoms of myalgia or improvement of serum levels of CoQ10 with supplementation. One study showed no benefit of CoQ10 supplementation when taken with statins. There were no risks of supplementation reported in any of the studies. IMPLICATIONS FOR PRACTICE:
CoQ10 supplementation might benefit those patients suffering from statin-induced myopathy as evidenced by the results of these studies. Supplementation of CoQ10 at a dose of between 30 and 200 mg daily has shown to have beneficial effects on statin myopathy with no noted side effects. Further research is necessary.
|
Authors | Nate Littlefield, Renea L Beckstrand, Karlen E Luthy |
Journal | Journal of the American Association of Nurse Practitioners
(J Am Assoc Nurse Pract)
Vol. 26
Issue 2
Pg. 85-90
(Feb 2014)
ISSN: 2327-6924 [Electronic] United States |
PMID | 24170646
(Publication Type: Journal Article, Review)
|
Copyright | ©2013 The Author(s) ©2013 American Association of Nurse Practitioners. |
Chemical References |
- Hydroxymethylglutaryl-CoA Reductase Inhibitors
- Vitamins
- Ubiquinone
- coenzyme Q10
|
Topics |
- Dietary Supplements
- Humans
- Hydroxymethylglutaryl-CoA Reductase Inhibitors
(adverse effects)
- Muscular Diseases
(chemically induced, drug therapy)
- Ubiquinone
(analogs & derivatives, blood, therapeutic use)
- Vitamins
(therapeutic use)
|