Orcein-positive material in Kupffer cells from the liver.

Abstract

Orcein-positive material in Kupffer cells obtained from 1,377 needle biopsies of the liver was studied for hepatitis B surface antigen (HBsAg). Fifty-five (57%) out of 96 cases with orcein-positive Kupffer cells had acute hepatitis, and 46 (84%) of these 55 were in the late stage of their illness. Orcein-positive material in Kupffer cells was not associated with HBsAg as evaluated by the immune peroxidase method. Orcein-positive material in Kupffer cells appears to consist mainly of lipofuscins developing in the course of acute hepatitis.

• Authors: C Uehara, M Sakurai, H Ishizu, N Mitsutani, T Koizumi
• Journal: Hepato-gastroenterology (Hepatogastroenterology) Vol. 32 Issue 5 Pg. 232-4 (Oct 1985) ISSN: 0172-6390 [Print] Greece
• PMID: 2416662 (Publication Type: Journal Article)

Chemical References

• Hepatitis B Surface Antigens
• Lipofuscin
• Oxazines
• PAcein

Topics

• Acute Disease
• Hepatitis (immunology)
• Hepatitis B Surface Antigens (analysis)
• Humans
• Kupffer Cells (analysis)
• Lipofuscin (analysis)
• Liver (pathology)
• Oxazines
• Staining and Labeling