Pacing failure due to flecainide acetate.

Abstract

Flecainide acetate is a recently introduced, class 1 antiarrhythmic agent that is highly effective in the treatment of ventricular and atrioventricular/nodal reentrant tachycardias. Although both intravenous and orally administered flecainide are known to cause an increase in the pacing threshold, an abrupt and potentially lethal rise in threshold causing failure of a properly functioning, newly implanted pacing system has not to our knowledge been described. We report such a case to stress the need for caution when using this drug in elderly pacemaker patients.

• Authors: P R Walker, M Papouchado, M A James, L M Clarke
• Journal: Pacing and clinical electrophysiology : PACE (Pacing Clin Electrophysiol) Vol. 8 Issue 6 Pg. 900-2 (Nov 1985) ISSN: 0147-8389 [Print] United States
• PMID: 2415944 (Publication Type: Case Reports, Journal Article)

Chemical References

• Piperidines
• Flecainide

Topics

• Aged
• Arrhythmias, Cardiac (etiology)
• Cardiac Pacing, Artificial (adverse effects)
• Flecainide
• Humans
• Male
• Piperidines (adverse effects)
• Tachycardia, Paroxysmal (drug therapy, therapy)