A new case of successful outcome of pregnancy in a carrier of homozygous type II (L99F) antithrombin deficiency.

Abstract

Inherited antithrombin deficiency is associated with an increased risk of venous thromboembolism. There is no consensus about pregnancy management in antithrombin deficiency patients because there are very few cases published in the literature. We report a successful pregnancy in a 32-year-old female carrier of a homozygous type II (L99F) antithrombin deficiency who developed a spontaneous deep vein thrombosis at the age of 27 years.

• Authors: Cristina Pascual, Carolina Muñoz, Ana R Huerta, Gloria P Rus, Virginia Ortega, Javier Corral, Jose L Diez-Martin
• Journal: Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis (Blood Coagul Fibrinolysis) Vol. 25 Issue 1 Pg. 74-6 (Jan 2014) ISSN: 1473-5733 [Electronic] England
• PMID: 24158114 (Publication Type: Case Reports, Journal Article)

Topics

• Adult
• Antithrombin III Deficiency (physiopathology)
• Female
• Humans
• Pregnancy
• Pregnancy Complications, Hematologic (physiopathology)
• Pregnancy Outcome
• Venous Thrombosis (physiopathology)