Novel oral anticoagulants: a focused review for stroke physicians.

Abstract

Novel oral anticoagulants provide an effective and convenient alternative to warfarin for stroke prevention in patients with atrial fibrillation. However, novel anticoagulants also present new challenges for stroke physicians, such as measurement of anticoagulant effect in emergency situations, use of thrombolysis in acute ischemic stroke, optimal timing of introduction of novel anticoagulants following acute ischemic stroke, and management of intracerebral hemorrhage. In this review, we propose pragmatic approaches to dealing with challenging management issues that will face stroke physicians who care for patients with acute stroke in the novel oral anticoagulant era.

• Authors: Emer R McGrath, John W Eikelboom, Moira K Kapral, Martin J O'Donnell
• Journal: International journal of stroke : official journal of the International Stroke Society (Int J Stroke) Vol. 9 Issue 1 Pg. 71-8 (Jan 2014) ISSN: 1747-4949 [Electronic] United States
• PMID: 24148753 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't, Review)
• Copyright: © 2013 The Authors. International Journal of Stroke © 2013 World Stroke Organization.

Chemical References

• Anticoagulants
• Benzimidazoles
• Morpholines
• Pyrazoles
• Pyridines
• Pyridones
• Thiophenes
• apixaban
• Rivaroxaban
• Dabigatran

Topics

• Administration, Oral
• Anticoagulants (administration & dosage)
• Benzimidazoles (administration & dosage)
• Child
• Dabigatran
• Humans
• Morpholines (administration & dosage)
• Pyrazoles (administration & dosage)
• Pyridines (administration & dosage)
• Pyridones (administration & dosage)
• Rivaroxaban
• Stroke (drug therapy)
• Thiophenes (administration & dosage)