Triple simultaneous primary invasive gynecological malignancies: a case report.

Abstract

Double gynecologic cancer (primary cancers in two organs) is relatively rare. However, triple gynecologic cancer (primary cancers in three organs) is extremely rare. We experienced a case of triple cancer, with primary cervical, endometrial and ovarian cancers, each showing different histopathological features. A 50-year-old woman with a preoperative diagnosis of cervical cancer stage Ib1 with a pathological diagnosis of mucinous adenocarcinoma underwent radical hysterectomy. The pathological diagnoses of the extracted masses were endometrioid adenocarcinoma in the uterine corpus and serous adenocarcinoma in the left ovary. Consequently, triple cancer was diagnosed. After the operation, six cycles of a paclitaxel/carboplatin regimen were administered, and no relapse of the cancers has been observed to date. To our knowledge, this is only the second case report in the international literature of concurrent gynecologic triple cancers of epithelial origin; that is, invasive cervical, endometrial and ovarian cancers, each with different histopathological features.

• Authors: Eriko Takatori, Tadahiro Shoji, Yuki Miura, Satoshi Takeuchi, Noriyuki Uesugi, Toru Sugiyama
• Journal: The journal of obstetrics and gynaecology research (J Obstet Gynaecol Res) Vol. 40 Issue 2 Pg. 627-31 (Feb 2014) ISSN: 1447-0756 [Electronic] Australia
• PMID: 24147606 (Publication Type: Case Reports, Journal Article)
• Copyright: © 2013 The Authors. Journal of Obstetrics and Gynaecology Research © 2013 Japan Society of Obstetrics and Gynecology.

Topics

• Adenocarcinoma (pathology, therapy)
• Endometrial Neoplasms (pathology, therapy)
• Female
• Humans
• Middle Aged
• Neoplasm Invasiveness
• Neoplasms, Multiple Primary (pathology, therapy)
• Ovarian Neoplasms (pathology, therapy)
• Uterine Cervical Neoplasms (pathology, therapy)