Abstract | BACKGROUND:
Pruritus can be defined as an unpleasant cutaneous sensation associated with the immediate desire to scratch. In particular external intimate zone could be hit by pruritus genitalis because of several reasons ( bacterial infection, fungal infection, stress, bad intimate behavior, synthetic intimate clothes). AIM: PATIENTS AND METHODS: Independent, randomized, double-blind, controlled trial in two University affiliated Italian Hospitals. 80 women, affected by aspecific pruritus genitalis with negative vaginal swab for bacterial or fungal infections or other pathogenic causes of itching, were selected and blindly treated by Dermoxen® Lenitiva cream or methylprednisolone aceponate 0.1% based cream. The main outcome measures were: the reduction of sensation of pruritus, evaluated by a visual analog scale (VAS) pain score, and improvement of intimate wellness sensation, and comfort during sexual intercourse, frequency and severity of adverse reactions. RESULTS: Significant reduction of itching sensation was verified for each treatment. CONCLUSIONS:
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Authors | D Carati, M Guido, A Malvasi, A Zizza, A Tinelli |
Journal | European review for medical and pharmacological sciences
(Eur Rev Med Pharmacol Sci)
Vol. 17
Issue 19
Pg. 2668-74
(Oct 2013)
ISSN: 1128-3602 [Print] Italy |
PMID | 24142616
(Publication Type: Comparative Study, Journal Article, Randomized Controlled Trial)
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Chemical References |
- Ointments
- Plant Extracts
- methylprednisolone aceponate
- Methylprednisolone
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Topics |
- Adult
- Double-Blind Method
- Female
- Genital Diseases, Female
(drug therapy)
- Humans
- Methylprednisolone
(analogs & derivatives, therapeutic use)
- Ointments
- Phytotherapy
- Plant Extracts
(therapeutic use)
- Pruritus
(drug therapy)
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