A focused review of the role of ketone bodies in health and disease.

Abstract

Ketone bodies are produced in the liver and are utilized in other tissues in the body as an energy source when hypoglycemia occurs in the body. There are three ketone bodies: acetoacetate, beta hydroxy butyrate, and acetone. Ketone bodies are usually present in the blood, and their level increases during fasting and starvation. They are also found in the blood of neonates and pregnant women. In diabetic ketoacidosis, high levels of ketone bodies are produced in response to low insulin levels and high levels of counter-regulatory hormones.

• Authors: Muhammad Akram
• Journal: Journal of medicinal food (J Med Food) Vol. 16 Issue 11 Pg. 965-7 (Nov 2013) ISSN: 1557-7600 [Electronic] United States
• PMID: 24138078 (Publication Type: Journal Article, Review)

Chemical References

• Acetoacetates
• Blood Glucose
• Acetone
• acetoacetic acid
• 3-Hydroxybutyric Acid

Topics

• 3-Hydroxybutyric Acid (blood, therapeutic use)
• Acetoacetates (blood, therapeutic use)
• Acetone (blood, therapeutic use)
• Alzheimer Disease (drug therapy)
• Blood Glucose (metabolism)
• Diabetic Ketoacidosis (blood)
• Female
• Health
• Humans
• Hypoglycemia (blood)
• Infant, Newborn (blood)
• Pregnancy (blood)
• Starvation (blood)