Abstract | BACKGROUND: Ca. 50% of Germans develop prediabetes in their lifetime. Though diabetes type 2 has been proven preventable, no screening for prediabetes has been implemented. DELIGHT was designed to assess if screening for individuals at risk and long-standing diabetes prevention is feasible in the setting of companies within the scope of the German legal health system. MATERIALS AND METHODS: In 5 companies employees with a waist circumference of ≥ 94 (men) and ≥ 80 cm (women) were offered a check-up. Those with fasting plasma glucose ≥ 100 mg/dl (IFG) or ≥ 140 mg/dl 2 h after oral glucose load (IGT) were followed for 3 years with an optional moderate lifestyle program during the first year and quarterly assistance for another 2 years. RESULTS: In 241 of 300 participants the self-measured waist circumference was confirmed as elevated. 3% had type 2 diabetes, while 37% had IFG (isolated in 96%) or IGT, of whom 91.4% (men) and 76.1% (women) had a metabolic syndrome. Within 3 years in those who had lost ≥ 1 kg, weight was reduced by 3.9 kg, risk factors were improved, and no case of diabetes had developed, while among those with weight loss of < 1 kg or weight gain, 10% of men and 5% of women had developed diabetes type 2. Screening for prediabetes did not increase the number or costs of drug prescriptions. CONCLUSIONS: Companies provide a suitable setting for screening for prediabetes. Long-term diabetes prevention is successfully feasible within the narrow financial frame of a legal insurance system without rise of costs.
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Authors | B-C Zyriax, B Letsch, S Stock, E Windler |
Journal | Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association
(Exp Clin Endocrinol Diabetes)
Vol. 122
Issue 1
Pg. 20-6
(Jan 2014)
ISSN: 1439-3646 [Electronic] Germany |
PMID | 24132568
(Publication Type: Clinical Trial, Journal Article, Multicenter Study)
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Copyright | © J. A. Barth Verlag in Georg Thieme Verlag KG Stuttgart · New York. |
Topics |
- Adult
- Aged
- Aged, 80 and over
- Diabetes Mellitus, Type 2
(epidemiology, prevention & control)
- Feasibility Studies
- Female
- Germany
(epidemiology)
- Glucose Intolerance
(epidemiology, prevention & control)
- Health Plan Implementation
- Health Promotion
(methods)
- Humans
- Life Style
- Male
- Middle Aged
- Private Sector
- Program Evaluation
- Risk Reduction Behavior
- Waist Circumference
- Weight Loss
- Weight Reduction Programs
- Young Adult
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