"Nocturnal seizures" in idiopathic pulmonary arterial hypertension.

Abstract

The usual differential diagnoses of nocturnal events in children include parasomnias, nocturnal seizures, nocturnal reflux (Sandifer syndrome), hypnic jerks, periodic limb movements of sleep, and sleep disordered breathing. We report a previously healthy young girl who presented to the sleep clinic for evaluation of nocturnal events which were diagnosed as medically refractory nocturnal seizures. It was not until a syncopal event occurred in the daytime, which prompted referral for cardiac evaluation, the diagnosis of idiopathic pulmonary arterial hyper-tension (IPAH) was made. Sleep physicians should consider IPAH in the differential diagnosis of nocturnal events in children.

• Authors: Anthony Izzo, Julia McSweeney, Thomas Kulik, Umakanth Khatwa, Sanjeev V Kothare
• Journal: Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine (J Clin Sleep Med) Vol. 9 Issue 10 Pg. 1091-2 (Oct 15 2013) ISSN: 1550-9397 [Electronic] United States
• PMID: 24127156 (Publication Type: Case Reports, Journal Article, Review)

Chemical References

• Carbolines
• Warfarin
• Tadalafil
• Epoprostenol
• treprostinil

Topics

• Carbolines (administration & dosage)
• Cardiac Output, Low
• Child, Preschool
• Diagnosis, Differential
• Drug Therapy, Combination
• Epoprostenol (administration & dosage, analogs & derivatives)
• Female
• Humans
• Hypertension, Pulmonary (complications, diagnosis, therapy)
• Oxygen Inhalation Therapy
• Parasomnias (complications, diagnosis)
• Seizures (complications, diagnosis)
• Severity of Illness Index
• Sleep Apnea Syndromes (etiology, physiopathology)
• Tadalafil
• Treatment Outcome
• Warfarin (administration & dosage)