Post-angioplasty far infrared radiation therapy improves 1-year angioplasty-free hemodialysis access patency of recurrent obstructive lesions.

Abstract

OBJECTIVE:

To explore the role of far infrared (FIR) radiation therapy for hemodialysis (HD) access maintenance after percutaneous transluminal angioplasties (PTA).

METHODS:

This was a prospective observational study. Eligible patients were those who received repeated PTA with the last PTA successfully performed within 1 week before the study enrollments. Consecutively enrolled patients undergoing successful HD treatments after PTA were randomly assigned to the FIR-radiated group or control group without radiation. FIR-radiated therapy meaning 40-minute radiation at the major lesion site or anastomosed site three times a week was continued until an end-point defined as dysfunction-driven re-PTA or the study end was reached.

RESULTS:

Of 216 participants analyzed, including 97 with arteriovenous grafts (AVG) (49 FIR-radiated participants and 48 control participants) and 119 with arteriovenous fistulas (AVF) (69 FIR-radiated participants and 50 control participants), the FIR-radiated therapy compared with free-radiated usual therapy significantly enhanced PTA-unassisted patency at 1 year in the AVG subgroup (16.3% vs. 2.1%; p < .01), but not the AVF subgroup (25.0% vs. 18.4%; p = .50), and this accounted for the overall improved patency rates (21.4% vs. 10.3%; p = .02).

CONCLUSIONS:

This study suggests FIR-radiated therapy improves PTA-unassisted patency in patients with AVG who have undergone previous PTA.

• Authors: C-C Lai, H-C Fang, G-Y Mar, J-C Liou, C-J Tseng, C-P Liu
• Journal: European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery (Eur J Vasc Endovasc Surg) Vol. 46 Issue 6 Pg. 726-32 (Dec 2013) ISSN: 1532-2165 [Electronic] England
• PMID: 24119468 (Publication Type: Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)
• Copyright: Copyright © 2013 European Society for Vascular Surgery. Published by Elsevier Ltd. All rights reserved.

Topics

• Aged
• Angioplasty, Balloon
• Arteriovenous Fistula (therapy)
• Arteriovenous Shunt, Surgical
• Female
• Graft Occlusion, Vascular (therapy)
• Humans
• Infrared Rays (therapeutic use)
• Male
• Middle Aged
• Prospective Studies
• Recurrence
• Regional Blood Flow (radiation effects)
• Renal Dialysis
• Vascular Patency (radiation effects)