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Intracameral injection of tissue plasminogen activator to treat severe postoperative fibrinous reaction in iridocorneal endothelial syndrome.

Abstract
Iridocorneal endothelial (ICE) syndrome is a primary endothelial abnormality that can cause a spectrum of iris changes, corneal edema, and glaucoma. Glaucoma secondary to ICE is difficult to manage because of the inflammatory reaction and fibrosis it can cause. We present a case of postoperative fibrinous reaction following endoscopic cyclophotocoagulation in ICE that caused aqueous tube shunt occlusion and high intraocular pressure. The condition was successfully managed with tissue plasminogen activator.
AuthorsBryan K Hong, Brian A Francis
JournalDigital journal of ophthalmology : DJO (Digit J Ophthalmol) Vol. 19 Issue 2 Pg. 21-3 ( 2013) ISSN: 1542-8958 [Electronic] United States
PMID24109245 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Fibrinolytic Agents
  • Tissue Plasminogen Activator
Topics
  • Anterior Chamber
  • Cataract Extraction (adverse effects)
  • Female
  • Fibrinolysis (drug effects)
  • Fibrinolytic Agents (administration & dosage)
  • Humans
  • Injections, Intraocular
  • Iridocorneal Endothelial Syndrome (surgery)
  • Lens Implantation, Intraocular (adverse effects)
  • Middle Aged
  • Postoperative Complications (drug therapy)
  • Tissue Plasminogen Activator (administration & dosage)
  • Treatment Outcome

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