Health-related quality of life in psoriatic arthritis patients in Spain.

Abstract

PURPOSE:

To describe the demographic and clinical characteristics, including health-related quality-of-life (HRQL), in patients with psoriatic arthritis (PsA).

METHODS:

287 patients from 18 Spanish centres were assessed. PsA severity was measured using the following criteria: (1) Psoriasis Area and Severity Index (PASI score 0-72, from low to high severity); (2) number of swollen and tender joints; and (3) Health Assessment Questionnaire (HAQ score 0-3 from low to high impairment in daily activities). HRQL assessment was performed using the following criteria: (a) EuroQol-5D (EQ-5D scores 1-3, with a higher score representing a worse HRQL), Visual Analogue Scale (VAS score 0-100, with a higher score representing a better HQRL) and (b) Short Form-36 (SF-36 score 0-100, with a higher score representing a better HRQL).

RESULTS:

24.7% of patients were treated with infliximab. In the two groups, 55.7% of the patients were male with a mean age of 52.40±12.53 years. The average number of swollen joints was higher in patients not receiving biological therapy than in those receiving treatment (2.98 vs. 1.54). The mean PASI score was 3.73±5.83, and there was no difference between groups. HAQ scores were higher in patients receiving infliximab than in those not receiving treatment (0.93 vs. 0.70). The mean EQ-5D scores in the two groups indicated a poorer status based on pain and inability to perform usual/daily activities. HRQL measured by VAS score mean was 60.41 ± 20.08, and there was no difference between the groups. The domains in the SF-36 suggesting poorer functioning in the two groups were the physical role (50.76 ± 43.43), physical pain (49.35 ± 25.69) and the overall physical component (37.88 ± 10.87).

CONCLUSIONS:

PsA is associated with an impaired HRQL characterised by physical pain and poorer functioning in daily activities.

• Authors: Jordi Gratacós, Esteban Daudén, Juan Gómez-Reino, José Carlos Moreno, Miguel Ángel Casado, Vicente Rodríguez-Valverde
• Journal: Reumatologia clinica (Reumatol Clin) 2014 Jan-Feb Vol. 10 Issue 1 Pg. 25-31 ISSN: 1885-1398 [Electronic] Spain
• PMID: 24099960 (Publication Type: Journal Article, Multicenter Study, Observational Study, Research Support, Non-U.S. Gov't)
• Copyright: Copyright © 2012 Elsevier España, S.L. All rights reserved.

Chemical References

• Anti-Inflammatory Agents, Non-Steroidal
• Antibodies, Monoclonal
• Infliximab

Topics

• Adult
• Aged
• Aged, 80 and over
• Anti-Inflammatory Agents, Non-Steroidal (therapeutic use)
• Antibodies, Monoclonal (therapeutic use)
• Arthritis, Psoriatic (drug therapy)
• Cross-Sectional Studies
• Female
• Humans
• Infliximab
• Male
• Middle Aged
• Pain Measurement
• Quality of Life
• Severity of Illness Index
• Spain
• Surveys and Questionnaires