HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Concentrations of murinoglobulin and alpha-macroglobulin in the mouse serum: variations with age, sex, strain, and experimental inflammation.

Abstract
Serum levels of murinoglobulin and alpha-macroglobulin were low in newborn mice but increased during the prepubertal development. The adult levels of the two inhibitors were higher in males than in females in 8 inbred strains tested. Gonadectomy at 2 w of age did not significantly affect the prepubertal rise in the levels not only of the above two inhibitors but of contrapsin and alpha-1-antiprotease. The gonadectomy, however, abolished the sex differences seen in the adult levels of these inhibitors. The levels of murinoglobulin and alpha-macroglobulin reached their minimum at 12 h after inducing inflammation and returned to normal at 24 h. Little change was observed in the levels of contrapsin and alpha-1-antiprotease under the same inflammatory conditions.
AuthorsK Yamamoto, Y Tsujino, A Saito, H Sinohara
JournalBiochemistry international (Biochem Int) Vol. 10 Issue 3 Pg. 463-9 (Mar 1985) ISSN: 0158-5231 [Print] Australia
PMID2409976 (Publication Type: Comparative Study, Journal Article)
Chemical References
  • Blood Proteins
  • Serpins
  • Serum Globulins
  • Trypsin Inhibitors
  • alpha 1-Antitrypsin
  • alpha-Macroglobulins
  • murinoglobulin
  • contrapsin
Topics
  • Age Factors
  • Animals
  • Blood Proteins
  • Female
  • Inflammation (blood)
  • Male
  • Mice
  • Mice, Inbred Strains
  • Pregnancy
  • Serpins
  • Serum Globulins (metabolism)
  • Sex Factors
  • Species Specificity
  • Trypsin Inhibitors (blood)
  • alpha 1-Antitrypsin
  • alpha-Macroglobulins (metabolism)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: