Abstract |
Serum levels of murinoglobulin and alpha-macroglobulin were low in newborn mice but increased during the prepubertal development. The adult levels of the two inhibitors were higher in males than in females in 8 inbred strains tested. Gonadectomy at 2 w of age did not significantly affect the prepubertal rise in the levels not only of the above two inhibitors but of contrapsin and alpha-1-antiprotease. The gonadectomy, however, abolished the sex differences seen in the adult levels of these inhibitors. The levels of murinoglobulin and alpha-macroglobulin reached their minimum at 12 h after inducing inflammation and returned to normal at 24 h. Little change was observed in the levels of contrapsin and alpha-1-antiprotease under the same inflammatory conditions.
|
Authors | K Yamamoto, Y Tsujino, A Saito, H Sinohara |
Journal | Biochemistry international
(Biochem Int)
Vol. 10
Issue 3
Pg. 463-9
(Mar 1985)
ISSN: 0158-5231 [Print] Australia |
PMID | 2409976
(Publication Type: Comparative Study, Journal Article)
|
Chemical References |
- Blood Proteins
- Serpins
- Serum Globulins
- Trypsin Inhibitors
- alpha 1-Antitrypsin
- alpha-Macroglobulins
- murinoglobulin
- contrapsin
|
Topics |
- Age Factors
- Animals
- Blood Proteins
- Female
- Inflammation
(blood)
- Male
- Mice
- Mice, Inbred Strains
- Pregnancy
- Serpins
- Serum Globulins
(metabolism)
- Sex Factors
- Species Specificity
- Trypsin Inhibitors
(blood)
- alpha 1-Antitrypsin
- alpha-Macroglobulins
(metabolism)
|